Saturday, March 22, 2014

Brain Restoration: ‘Too Good To Be True’ for Addiction and Disease?

Could megadoses of energy-giving NAD—which allegedly relieves withdrawal symptoms, flushes out stored drugs in the body and replenishes balance in the brain—really be the cure-all for addiction as well as many other diseases and mental health disorders?

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When Paul decided again it was time to do something about his drug addiction, he knew the usual routes wouldn’t work. While using a variety of substances for at least two-thirds of his life – injecting heroin in the last 20 years of it - he also became a veteran of just about every traditional rehab/detox program in the book. Twelve to be exact; with no permanent results or positive outcomes to speak of.

Hearing the remarkable claims from a Brain Restoration Therapy outpatient clinic immediately sent him into skeptic mode: This is too good to be true. How can I kick drugs with just an infusion of some concoction? What about withdrawal? Side effects? And, if it really works, will it last? Sounded far too simple for this jaded, somewhat cynical, pushing-60 drug addict.

Figuring he had nothing to lose, he called and arranged a free consultation. After listening to details of their success rate and impressed with assertions of little or no withdrawal symptoms, he signed up for the treatment - albeit with some reluctance. His wife’s divorce threat had something to do with enrolling, but it was more about life hitting bottom one more time.

Groggily arriving at the crack of 9 am the next day, a warmly friendly nurse in navy blue scrubs hooked him up to an IV. Told that all he needed to do was relax, he settled into the oversize leather lounge chair. If nothing else he’d be able to listen to music, watch a few videos, and read a bit, he thought. Observing the slow drip of clear liquid entering his veins, he listlessly wondered what he would do next if this latest treatment failed.

At the end of the first eight-hour treatment, Paul says he already felt different. He couldn’t quite explain it, he recalls, but his mind was clearer. He felt energized. More alive. And definitely more present.

Returning daily for nine more treatments, he noticed a growing list of undeniable and rather dramatic changes. His outlook was more positive and he was optimistically able to imagine a future for himself, one he’d stopped envisioning years ago. His mind was as sharp as it had been prior to years of drug use.

The best part, he says, true to the claims, there were few or no withdrawal symptoms therefore no need for a replacement drug to get him through yet another grueling detox. He also realized he had no cravings, the primary cause of his continued bouts of relapse. His disbelief completely gone, he recalls, he concluded he was drug free.

But would it last?

Ann Rodgers, the Director of Brain Restoration Therapy, meets me at the door of the Center for Health and Wellbeing in San Diego, CA., where the clinic operates under medical supervision. It’s difficult to not get caught up in her animated explanation of the benefits of this program. “The treatment utilizes a megadose of NAD [Nicotinamide Adenine Dinucleotide is a co-enzyme of niacin that is the key fuel for energy production in every cell of the body] in an IV form, and it’s clinically proven with a 90% no-craving statistic,” she excitedly offers.

Listening quietly as she rapidly fires glowing statistics in my direction, my skeptical mind revs into full gear. “With literally no reported side-effects," she says, “the protocol reduces withdrawal symptoms by 70-80% without using replacement drugs, and restores the patient's clarity and well-being to pre-use levels. Six to ten days of treatment is like a seven or eight month jump-start to recovery.” All this expounded with the tone of a bragging parent.

Rodgers tells me that although relatively new to America, NAD treatment has been successfully used in South Africa since 1961, with centers there reporting more than 22,000 people treated. [Rodgers could not provide any research report from South Africa to confirm this, only a report from individual clinicians who treated patients with NAD. Separately, I could not confirm the 22,000 figure.]

The first NAD clinic to open in the States was in Springfield, Louisiana, founded by psychotherapist Paula Mestayer, M.Ed, LPC, FAPA, along with her psychiatrist husband Richard. The couple discovered the treatment when their 16-year-old adopted daughter became addicted to alcohol and found her way into NAD treatment. Thrilled to see her positive results, they conducted their own research and in 2001, putting aside their cumulative years of treating addicts with therapy, they opened the Springfield Wellness Center on a private 500-acre estate. They claim to have treated more than 1,000 patients since then with NAD.

Springfield Wellness Center's ten day addiction detox, Mestayer asserts when I contact her, has been used successfully on people hooked on prescription drugs, alcohol, opiates, benzos, stimulants, cocaine, marijuana, suboxone, and methadone.

Mestayer noted in our interview that “like a thumb print, all brains are unique, so this protocol is more like an art than a science.” Each patient, she pointed out, responds differently to NAD, with one factor being their type of addiction. She therefore adjusts the dosage and prescribes booster NAD treatments when necessary, especially when a patient feels vulnerable or if any cravings return. “I always emphasize that there may be a period of time where they need maintenance, either by an occasional booster or other means of support. Some patients have gone nine years without needing a booster, but many do.” Mestayer generally prescribes oral NAD as a supplement to the IVs, on the grounds that the more NAD that builds up in an addict’s system, the less prone he or she is to succumbing to cravings

Mestayer emphasizes that the treatment is “not a cure, but rather maintenance,” and notes that it remains a mystery as to why NAD works more successfully on some addictions than others. “The highest success rate is on alcohol and opiate users,” she says. “The only failures are people who were using during the treatment or not committed to their maintenance.” Even so, she like Rodgers encourages all patients to seek therapy and support groups to address underlying psychological issues.

In California, I asked Rodgers if the treatment is just a substitute “high.” Rodgers countered with “it’s a state of well-being that allows the client to feel content with their life, so many don’t even consider going back to being an addict, no desire for that miserable life anymore. It’s as if they become themselves again, back to their natural state, seeing themselves as a different person, separate from being an addicted person. It’s not just a detox; it’s a total state of sobriety."

With only a handful of other U.S. clinics in existence, the technology has yet to become familiar to most of the recovery community. Even so, Ann Rodgers says she is certain that once knowledge of NAD spreads, it will be seen as a revolution in addiction treatment. “[Members of] the AA community have been resistant to it at first, but once they read the evidence and witness the results, they embrace it,” she claims.

Her San Diego clinic is modern, serenely comfortable and well-appointed. Located on the first floor of the larger health center, it’s been open for over three years and has treated nearly 40 patients. Rodgers recently opened another facility in Los Angeles, CA, at the Center for Optimum Health.

HOW THE TREATMENT WORKS

Dr. Janette Gray, a California licensed internist and a pioneer in combining allopathic and holistic medical approaches, is the center’s medical director. Board certified in Holistic Integrative Medicine, she worked for years in the prison system helping inmates get off drugs and has extensive experience with the agonies of drug withdrawal. “Seizures, nausea and vomiting, intense sweating and physical pain are standard, but that is greatly minimized with this program,” she tells me. “The most common withdrawal symptom is feeling a little bit flu-ish…[which] passes quickly.”

Gray rattles off to me a scientific explanation behind the BR treatment. The protocol, she says, employs a proprietary NAD formula administered by IV. NAD is an element that reacts with oxygen in the cell’s mitochondria in order to create energy for movement, breathing, heartbeat, blood pumping, digesting food, brain functions, and generally living life. It is available in low doses over the counter.

Studies have found that those with extremely low NAD levels (which can be present even at birth) are far more vulnerable to addiction as well as other diseases and to chronic physical conditions. There is a preponderance of low levels of NAD present in Western society as it is mostly lost in cooking and food processing. What little remains is broken down by stomach acid, degraded before it’s absorbed from the digestive tract.

When the clinic’s all-natural NAD is received directly through an IV, the nutrients bypass the stomach and go directly to the receptors in the brain, Gray tells me. According to Gray, this immediately produces palpable positive results as the nutrients bathe the brain in a continuous pool of natural and highly therapeutic co-enzymes.

Since NAD is a detoxifier, it takes days (rather than weeks or months), to flush out stored drugs from the body and its organs, replenish balance in the brain, and reverse damage. Results can be mental clarity, cognitive function increase, focus and concentration returns, more energy, better
mood, positive outlook. And this happens cold turkey.

Friday, March 21, 2014


Authorities Issue Warning About Deadly Street Drug, Fentanyl


Posted: Mar 20, 2014 4:30 PM EDTUpdated: Mar 20, 2014 4:30 PM EDT


MEDIA, Pa. -

District Attorney Jack Whelan, Marcus Hook Police Chief John Ireland and the Delaware County Medical Examiner Dr. Fredric Hellman have issued a warning regarding Fentanyl, a deadly, synthetic opioid narcotic that has claimed the life of a Delaware County woman.

Delaware County Medical Examiner Dr. Fredric Hellman said toxicology results returned on March 19 indicated that the recent death of a 30-year-old Marcus Hook woman was the result of the intravenous administration of pure Fentanyl. The name on the packet is "Black Dahlia," and the substance was packaged in a blue glassine packet with red lettering. According to Dr. Hellman, this is the first case in 2014 involving a death from pure Fentanyl. Fentanyl can come in the form of powder, pill or patch and has been known to be snorted or injected into the bloodstream. Authorities are warning the community that the use of this lethal drug will result in death.

"These drugs are manufactured in clandestine labs by criminals, and every single packet has the potential to kill the user," warned District Attorney Jack Whelan. "Those who believe they are purchasing heroin end up with a much more dangerous drug that is 100 percent pure and, when ingested, rapidly shuts down the central drive for breathing, resulting in death."

The Delaware County Heroin Task Force continues its efforts to educate and prevent the use of heroin and abuse of prescription drugs. "We are moving forward on many fronts to combat the heroin epidemic that has plagued Delaware County," said District Attorney Jack Whelan, chairman of the Heroin Task Force. "We are determined to do everything possible to protect our children, our families and our communities from the devastating effects of drug addiction." For more information visit the Heroin Task Force website at www.co.delaware.pa.us.

Residents who have any information concerning illegal drugs should contact the Marcus Hook Police Department at 610-485-1611 or the Delaware County Criminal Investigation Division at 610-891-4700



MARCH 21 v 30 TWELVE STEPPING WITH POWER IN THE PROVERB

No human wisdom or understanding or plan
can stand against the Lord.

STEP 3 -Made a decision to turn our will and our lives over to the care of God as we understood God.


Did you ever notice when in active addiction that everything in your life is falling apart . No matter how hard you try to make sense of the insanity that is your life you keep asking yourself what  am I doing wrong  ,well at least I did. I would always justify the insanity by lying to myself and convincing myself someone upstairs hates me or someone put a curse on me . Wow the excuses I had ! It took a lot of heartache , confusion , pain , and homelessness to hit the bottom. I am going to make this simple so you wont have to suffer as much as I did , and I hope you hear this message take it to heart so you wont lose it all like I did. Read the Proverb and commit step three , that's the answer ! You sincerely and whole heartily follow these two , God will Help and fix you ! 

Matthew chapter 10 v 38 - Those who do not take up their cross and follow in my STEPS are not fit to be my disciples .

Republicans Who Oppose Mandatory Minimum Sentences Say They’re Costly, Ineffective


Republicans, who have traditionally taken a tough approach on crime, are increasingly opposing mandatory minimum sentences, The New York Times reports. They see the sentences as ineffective, as well as too costly and punitive.

Fiscal conservatives are looking to save billions of dollars in the federal budget by closing prisons and releasing inmates who no longer appear to pose a threat to society. Religious conservatives view sentencing reform as a way to offer compassion and to reunite families.

Many Republicans and Democrats agree mandatory minimum sentences should be reduced, the newspaper notes. Attorney General Eric Holder is pushing to eliminate mandatory minimum sentences for nonviolent drug crimes. He is joining with libertarian Republicans, including Senator Rand Paul of Kentucky, in this effort.

Last week, Holder testified in favor of changing federal guidelines to reduce the average sentence for drug dealers. He told the United States Sentencing Commission the Obama Administration supports changing guidelines to reduce the average drug sentence by about one year, from 62 months to 51 months.

The proposed changes would reduce the federal prison population by about 6,550 inmates over the next five years. Currently, half of the 215,000 inmates in the federal prison system are serving time for drug crimes.

Republicans and Democrats in the Senate are discussing combining two bills on sentencing reform. One would give judges more leeway to depart from mandatory minimum sentences in lower-level drug cases, reduce mandatory sentences for other drug offenses, and make the 2010 law that reduced the disparity between cocaine and crack-cocaine sentences retroactive.

A second bill would establish a skills training and early release system for people who are incarcerated, but who are considered to be at low risk for committing another offense.
Teen Inhalant Use Decreasing: Government Report


By Join Together Staff | March 20, 2014 | Leave a comment | Filed in Drugs &Youth

Fewer American teens are abusing inhalants, such as spray paint, glue and gasoline, according to a new government report. The number of teens ages 12 to 17 who used inhalants dropped from 820,000 in 2011, to about 650,000 in 2012.

The Substance Abuse and Mental Health Services Administration (SAMHSA), which released the findings, defines inhalants as “liquids, sprays and gases that people sniff or inhale to get high or to make them feel good,” UPI reports.

“This downward trend of inhalant use in adolescents is very encouraging,” Pamela S. Hyde, administrator of the SAMHSA, said in a statement. “Nevertheless, we must all continue our efforts to raise awareness about the dangers and health risks of this deadly and addictive problem among our youth.”

When inhalants are breathed in through the nose or mouth in a variety of ways they are absorbed quickly through the lungs into the bloodstream and the user experiences a rapid but short-lived intoxication.

There are hundreds of household products on the market today that can be misused as inhalants. Examples of products kids abuse to get high include model airplane glue, nail polish remover, cleaning fluids, hair spray, gasoline, the propellant in aerosol whipped cream, spray paint, fabric protector, air conditioner fluid (freon), cooking spray and correction fluid.

These products are sniffed, snorted, bagged (fumes inhaled from a plastic bag), or “huffed” (inhalant-soaked rag, sock, or roll of toilet paper in the mouth) to achieve a high. Inhalants are also sniffed directly from the container.

Within seconds of inhalation, the user experiences intoxication along with other effects similar to those produced by alcohol. Alcohol-like effects may include slurred speech, an inability to coordinate movements, dizziness, confusion and delirium. Nausea and vomiting are other common side effects. In addition, users may experience lightheadedness, hallucinations, and delusions.

Compulsive use and a mild withdrawal syndrome can occur with long-term inhalant abuse. Additional symptoms exhibited by long-term inhalant abusers include weight loss, muscle weakness, disorientation, inattentiveness, lack of coordination, irritability, and depression.

Thursday, March 20, 2014



MARCH 20 v 3 TWELVE STEPPING WITH POWER IN THE PROVERB



Avoiding a fight is a mark of honor;
only fools insist on quarreling.

STEP 10 - Continued to take personal inventory and when we were wrong promptly admitted it.

 
As I get older the more and more I realize the proverb is right . Why are we so hell bent on proving our point. Back in the day not so long ago I knew everything and you could not tell me nothing . You could have been a world renown expert and I would find a reason to argue. Its ok too want to be right but if you don't have all the facts you need to make your point and don't push the person your haggling with they will eventually see the truth if they are the one at fault . It is not your job to beat it into their heads . The truth will always win out ! When we are wrong we need to man up and admit it that is called maturity and that is what us sober folks do. It will keep your mind and heart free of negativity , resentment , anger , bitterness , and denial .These are all fatal triggers that can push anyone into relapse.




JAMES CHAPTERP 1 v 19 v20 Understand this, my dear brothers and sisters: You must all be quick to listen, slow to speak, and slow to get angry.Human anger does not produce the righteousness God desires.

Teens will be teens. They sleep late, fail a test here and there or get uncharacteristically moody. But what if these behaviors are happening more often than usual, or all at the same time? You know your teen better than anyone, but it is important to know what to look for if you suspect he or she may be abusing medicine.
  1. Health concerns. Keep an eye out for changes in your teen’s physical health, like constricted pupils, nausea or vomiting, flushed skin or dizziness. Look further into anything that seems strange.
     
  2. Changes in behavior. The signs of medicine abuse aren’t always physical. Look for changes in behavior – like sudden changes in relationships with their family or friends, anxiety, erratic mood swings or decreased motivation. It’s no secret that teens can be moody, but be on the lookout for drastic differences in the way your child behaves.
     
  3.  Home-related signs. If you’ve noticed belongings  disappearing around the house, or found some unusual objects appearing – like straws, burnt spoons, aluminum foil or medicine bottles – this could be a sign of medicine abuse. Count – and lock up – the medicine you have in your home and safely dispose of any expired medicine.
     
  4. Trouble in school. Take note of how your teen is doing in school, including any change in homework habits and grades. A rapid drop in grades, loss of interest in schoolwork and complaints from teachers could be indicators that there’s a problem.
     
  5. Things just seem off. You know your child better than anyone and you know when something’s not right. Trust your gut, and talk to your teen about your concerns. 
With one in four kids reporting abuse of prescription drugs in their lifetime, it’s important to take action right away if you do suspect medicine abuse. Don’t be afraid to talk – and listen – to your teen, work through things together and get help if necessary.

 

Vaporizers Gain Popularity Among Marijuana Smokers

By Join Together Staff | March 18, 2014 | 1 Comment | Filed in Drugs

A growing number of marijuana smokers are choosing to use vaporizers, which are similar to e-cigarettes, according to USA Today. The popularity of the devices is changing the way marijuana is packaged and sold in states where it is legal.

The vaporizers, known as “vape pens,” are compact and portable. Steve DeAngelo, a marijuana entrepreneur and activist who founded the Harborside Health Center medical marijuana dispensary in Oakland, California, says his dispensary does about half of its business in raw marijuana leaf or flowers. The rest are sold as edibles or concentrates, some of which are prepackaged for use in vape pens. “The percentage of raw (pot) flowers we sell has been dropping steadily,” he said. “The percent of extracts and concentrates … has been rising steadily.” Some vape pens use concentrated marijuana extractions, while others use marijuana leaves and flowers.

“This really portends the next generation of marijuana use,” John Lovell, a Sacramento attorney and lobbyist for the California Narcotics Officers’ Association and California Police Chiefs Association, told the newspaper. His group is concerned about the high-strength concentrates used in vape pens. Concentrates can be composed of as much as 80 percent or 90 percent THC, the psychoactive ingredient in marijuana.

Others are concerned that vape pens allow teens to smoke marijuana without being detected, because the pens leave no odor.

OxyContin Manufacturer Tests Tamper-Resistant Form of Hydrocodone

By Join Together Staff | March 18, 2014 | Leave a comment | Filed in Prescription Drugs & Prevention


The maker of OxyContin announced promising results from a study of a tamper-resistant form of hydrocodone, The Washington Post reports. The Food and Drug Administration (FDA) has been criticized for approving Zohydro ER (extended release), a pure form of hydrocodone that is not tamper-resistant.

Purdue Pharma, which manufactures OxyContin, said it will soon seek FDA approval for its version of an extended-release form of hydrocodone. The company says its version is difficult for a person to crush, in order to inject or snort the drug. In 2010, the company reformulated OxyContin to make it harder to crush or dissolve.

The new study showed a majority of patients with chronic low back pain treated once daily with the hydrocodone drug experienced at least a 30 percent improvement in pain intensity, compared with a placebo. Almost half achieved a 50 percent improvement.

“This is another step forward in our efforts to develop therapeutic options for use by chronic pain patients that are designed to be unattractive to drug seekers,” Gary L. Stiles, the company’s Senior Vice President of Research and Development, said in a statement.

Last week, West Virginia Senator Joe Manchin called on Health and Human Services Secretary Kathleen Sebelius to overrule the FDA decision to approve Zohydro ER. Late last year, Manchin and three other senators wrote to the FDA, saying they disagreed with the agency’s decision to approve the drug. In October, the FDA approved Zohydro for patients with pain that requires daily, around-the-clock, long-term treatment that cannot be treated with other drugs. Drugs such as Vicodin contain a combination of hydrocodone and other painkillers such as acetaminophen.

In December, the attorneys general from 28 states asked the FDA to reassess its decision to approve Zohydro.

Study Finds Alcohol Deaths Most Likely to Impact Working-Age Adults

By Join Together Staff | March 18, 2014 | Leave a comment | Filed in Alcohol

The majority of alcohol-related deaths in the United States occur among working-age adults, a new government study concludes. Adults ages 20 to 64 account for more than two-thirds of these deaths.

The study by the Centers for Disease Control and Prevention (CDC) found in the 11 states studied, alcohol caused a median of 1,650 deaths annually between 2006 and 2010, HealthDay reports.

“It’s really important to drive home that excessive alcohol use is a leading cause of preventable death,” lead author Katherine Gonzales said. “It really is right up there with tobacco and physical inactivity, especially among working-age adults.”

The study included accidental alcohol-related deaths such as car crashes, firearm injuries, drownings and occupational injuries, as well as illnesses such as liver disease, stroke, high blood pressure, cancer, and fetal alcohol syndrome.

The CDC researchers found men were much more likely than women to die of alcohol-related causes. While the most alcohol-related deaths occurred among whites, deaths linked to excessive drinking were more likely among blacks, American Indians and Alaska natives.

Teens’ Definition of “Designated Driver” Can Be Loose, Survey Finds

By Join Together Staff | March 19, 2014 | Leave a comment | Filed in Alcohol & Youth


Teens’ definition of a “designated driver” can be loose, according to a new survey. About one in five teens say their designated person is allowed to have “a little” alcohol or other drugs, as long as they aren’t too impaired to drive.

The survey found 4 percent of teens describe their designated driver as the most sober person in the group, Bloomberg News reports. One in 10 teens who said they have never driven under the influence of alcohol admitted to driving after having a drink.

The survey, conducted by Liberty Mutual and Students Against Destructive Decisions (SADD), calls attention to risky behaviors by young people, the article notes. Teens “seem to think that unless they’re really falling-down drunk, that it’s OK for them to drive,” David Melton, Managing Director for Global Safety at Liberty Mutual, told Bloomberg News.

According to the National Highway Traffic Safety Administration, the driver was intoxicated in about 18 percent of fatal crashes involving drivers ages 16 to 20 in 2011.

The survey included 2,537 students in 11th and 12th grades. U.S. drivers with a blood alcohol concentration above .08 grams per deciliter are considered alcohol-impaired. “Long before you’re at .08, you’re definitely impaired in terms of your judgment,” Melton said. “You may not be over the legal limit, but you are driving with a buzz on and that’s not a good thing.”

In a statement, Stephen Gray Wallace, Senior Advisor for Policy, Research and Education at SADD, said, “With teens reporting these lax definitions of what it means to be ‘under the influence,’ a zero tolerance approach is the only answer to prevent potential tragedy. The parents and community have a responsibility to initiate and maintain an open dialogue with teens about exactly what driving under the influence means.”

Monthly Number of Federal Drug Defendants Drops to Lowest Level in 14 Years

By Join Together Staff | March 19, 2014 | Leave a comment | Filed in Drugs, Government, Legal & Legislation

Soon after Attorney General Eric Holder began making changes to drug laws, the number of drug defendants charged by the federal government dropped in January to its lowest monthly level in almost 14 years, according to a new report.

The report, by Syracuse University, found there were 1,487 new drug prosecutions in January 2014, down 7.8 percent from December, and down 11.5 percent from January 2013. “The number observed during the most recent six month period appears to be the lowest seen since the end of the Reagan Administration,” the researchers noted.

The drop in prosecutions follows the launch of Holder’s “Smart on Crime” initiative, The Huffington Post reports. The initiative’s goals include prioritizing prosecution to focus on the most serious cases, reforming sentencing to eliminate unfair disparities and reduce overburdened prisons, and pursuing alternatives to incarceration for low-level, non-violent crimes.

A spokeswoman for the Justice Department, Ellen Canale, told The Huffington Post, “It makes sense to reserve the harshest sentences for the most serious drug offenders. The department’s charging policies are aimed at empowering federal prosecutors to consider the individual circumstances of each defendant in order to determine what outcome best improves public safety.”

Last week, Holder testified before the United States Sentencing Commission in favor of changing federal guidelines to reduce the average sentence for drug dealers.

FDA Commissioner: Zohydro Offers Unique Option to Treat Pain

By Join Together Staff | March 19, 2014 | 1 Comment | Filed in Government & Prescription Drugs

Food and Drug Administration (FDA) Commissioner Margaret Hamburg defended the agency’s decision to approve the pure hydrocodone drug Zohydro ER (extended release). At a Senate hearing, Hamburg said, “If appropriately used, it serves an important and unique niche with respect to pain medication and it meets the standards for safety and efficacy.”

Speaking before the Senate Health, Education, Labor and Pensions Committee, Hamburg acknowledged Zohydro is a powerful drug. She noted that unlike other hydrocodone drugs, Zohydro does not contain acetaminophen, which can be toxic to the liver.

Zohydro is designed to be released over time, and can be crushed and snorted by people seeking a strong, quick high. “I would love if we had abuse-deterrent formulations that were actually meaningful and effective at deterring abuse in all instances. We are moving in that direction,” Hamburg said. “Right now, unfortunately, the technology is poor.”

The FDA’s decision to approve Zohydro has been criticized by some legislators and public health groups, Reuters reports. Hamburg has received letters protesting the decision from 28 state attorneys general and four senators, among others.

Law enforcement agencies and addiction experts predict approval of the drug will lead to an increase in overdose deaths.

Zohydro was approved for patients with pain that requires daily, around-the-clock, long-term treatment that cannot be treated with other drugs. In December 2012, a panel of experts assembled by the FDA voted against recommending approval of Zohydro ER. The panel cited concerns over the potential for addiction. In the 11-2 vote against approval, the panel said that while the drug’s maker, Zogenix, had met narrow targets for safety and efficacy, the painkiller could be used by people addicted to other opioids, including oxycodone.

Wednesday, March 19, 2014

MARCH 19 v 11 TWELVE STEPPING WITH POWER IN THE PROVERB

Sensible people control their temper;
they earn respect by overlooking wrongs.

STEP 4 - Made a searching and fearless moral inventory of ourselves.

Someone told me along time ago that anger undealt with becomes resentment and in return we become bitter . When working step four get ready to stir up some pretty heavy stuff. The tough part is we take stuff sweep it under a rug but that does not mean its not there . You are gonna have to dig deep on this one and be brutally honest with yourself and your sponsor. If we don't learn how to deal with and properly dispose of anger then we and everybody around us will suffer . Have you ever been around someone who is bitter they hate everything and everybody .They are the Kings and Queens of cynicism and self pity .They can and will suck the joy and life out of you . They are the people you cant stand being with .Are you one of those bitter joy killers ,if you are follow the Proverb and the step. Not everyone in your life has to be punished because of your undealt with resentments and anger. Show mercy and start controlling your anger and turn the other cheek.



JAMES CHP 1 v 19 v20 Understand this, my dear brothers and sisters: You must all be quick to listen, slow to speak, and slow to get angry.Human anger does not produce the righteousness God desires.

Getting to Rehab
RIDGWAY, ELK COUNTY PA - Drugs are something police everywhere have to deal with almost everyday.

"When I first moved here, there wasn't any. We didn't have that. I raised my kids here and it's gotten worse since then" said Ridgway resident Ketta Melzer.

"There is a real problem in this county of drug and alcohol use and abuse" added Salvation Army Lt. Esther Wilson.

She says the Ridway Salvation Army is now offering transportation to those seeking rehabilitation at one of their facilities throughout the country. The Salvation Army has over 150 and serves tens thousands of people each year.

" It is a 6 month program. It is in house. You get your rooming, your board and everything provided for you and it's no cost" she said.

The Salvation Army says since the transportation program began about a month ago they've already had someone, who was near overdosing, go to rehab.

"I believe in it. Threes a lot of good success cases that come out of it" said Wilson.

To get information on the program you can call (814)772-0485. They will give you the numbers you need to call to see if their is space for you at a center and then, they will help you get there and get clean.

Tuesday, March 18, 2014



MARCH 18 v18 TWELVE STEPPING WITH POWER IN THE PROVERB

Flipping a coin can end arguments;
it settles disputes between powerful opponents



STEP 3 - We made a decision to turn our wills and our lives over to the care of God.

Stop fighting with everybody including yourself. The Proverb mentions flipping a coin it settles disputes between powerful opponents and all I can think about is every single sport s game in the world . it goes too show you that Gods big book is a must for life and it contains all the answers you need for now and after your dead . Still trying to control the world and everybody else s well there's way too much stress for that , start focusing on you and NO you don't know everything ! That,s ok though that's why its called recovery , if want our lives back we have to let the old life go .When we do God will help up build a new one !
Tuesday, March 18th  
7:00 – 8:30pm
At The Council office, Unit 12

Please pass along the attached flyer to anyone you feel would benefit from this program.  As always, you must register yourself or your group ahead so that we may be prepared with enough materials and food/beverages.  If you have any questions, please let me know!

Thank you,


Jessica Schwartz
Volunteer Coordinator & Prevention Specialist
The Council of Southeast Pennsylvania, Inc.
252 West Swamp Road, Unit 33
Doylestown, Pennsylvania 18901
(800) 221-6333 - 24 Hour Information Line

myrecovery.com


Daily Quote

"What you are aware of you are in control of; what you are not aware of is in control of you." - Anthony De Mello


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Monday, March 17, 2014

MARCH 17 v 1 TWELVE STEPPING WITH POWER IN THE PROVERB

Better a dry crust eaten in peace
than a house filled with feasting—and conflict.

STEP 9 - Made direct amends to such people wherever possible, except when to do so would injure them or others.

Better to live in a house with nothing and have peace ! Conflict is a number one trigger for a lot of folks . When all hell is breaking lose at home sometimes its a good idea to step out of the situation call your sponsor or hit your knees until the craziness start to settle down . Once the smoke settles get rid of the source of conflict by committing step nine . Remember when we were out there doing our thing we caused a lot of heartache to the ones we live with . That heartache has destroyed our credibility and our loved ones who are victims of our insanity will have a lot of resentment and bitterness towards us . We have to earn there respect and trust and that is not going to happen overnight . They will need the most time to heal so be patient with them and try and see it from their point of view don't push and get angry like the old days. Love them unconditionally like they did for you even though your every other word was lie and you cannot count on your hands how many times you robbed them .


Matthew chapter 10 v 38 - Those who do not take up their cross and follow in my STEPS are not fit to be my disciples .

Staying Cool With Glutamate
Can an over-the-counter supplement now becoming popular for mental health and mood elevation help a person stay sober? The early research is promising.

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03/10/14



Most addicts will tell you that it’s easier to get sober than it is to stay sober. And, the more we learn about the neurobiology of addiction, the more addiction treatment specialists are inclined to say that relapse is a part of recovery.

Do addicts have to “white knuckle” it in order to get sober and stay clean? Yes, replacement and anti-craving medications exist, but many still suffer from generally poor outcomes. Replacement therapies for opioid addiction, such as methadone and buprenorphine, and for nicotine addiction are widely accepted. Alcoholics have naltrexone and acamprosate. However, all these are substance-specific, which is a disadvantage to using them to treat addicts who have more than one substance use disorder. Also there are no FDA-approved medications for treating addiction to cocaine and other stimulants. 

Peter Kalivas, a professor and researcher at the Medical University of South Carolina, has been studying the role of glutamate—a ubiquitous excitatory neurotransmitter in the brain—in addiction for over a decade. He believes that addicts can’t learn how to improve or alter their behavior because their substance use has actually impaired a critical brain circuit involving glutamate, one that allows them to translate the desire to change into action.

He’s not alone. The glutamate homeostasis hypothesis of addiction has not only gained traction in the lab in the past 15 years, but in the past five years, hundreds of clinical trials have ramped up with a focus on attempting to heal those damaged glutamate circuits using NAC. NAC, or N-acetylcysteine, is a precursor of the naturally occurring amino acid cysteine, and it is one particular compound that has shown immense clinical promise in treating all sorts of disorders, but especially compulsive ones like addiction. NAC is not found in food, but when taken as a supplement, it breaks down into cysteine and then, glutathione—a powerful antioxidant. What’s more, cysteine is essential to maintaining optimal levels of glutamate.

You might have seen NAC at your local Whole Foods, in fact—it’s a common supplement. It received FDA approval in 1963, and has been used since to treat symptoms of bronchitis, COPD and Tylenol overdoses, among many other diverse, off-label uses. It has gained attention in recent years as scientists learn more about its role in addiction—and preventing relapse.

Preliminary clinical studies have shown the promise of NAC in terms of safety, tolerability, and potential efficacy for encouraging abstinence from cocaine, nicotine, and cannabis. There are hundreds of clinical trials underway in the US studying NAC in the treatment of various disorders, including addiction to alcohol, cocaine, marijuana, nicotine, and methamphetamine, and for behavioral addictions, namely gambling. And, with trials underway for Alzheimer’s and Parkinson’s diseases, autism, compulsive and grooming disorders, schizophrenia, depression, and bipolar disorder—well, it makes NAC one of the most promising drug candidates in neuropsychiatry.

Glutamate homeostasis

A growing body of research has linked changes in the glutamate neurotransmitter system to addiction. When addicts use, they deplete this chemical, which is essential for transmitting signals from the cortex to the nucleus accumbens. The cortex can be thought of as the decision-making center of the brain, while the nucleus accumbens—which is also involved in the dopamine circuit—is the habit area. In addicts, this circuit becomes weak at best, broken at worst. “Even though they know it’s bad, they can’t use this information to change their behavior effectively,” Kalivas says. Because they can’t update their “habit” in response to different instructions from the cortex, they keep on using despite their own better judgment.

The glutamate system maintains a balance of synaptic—between two neurons—and extracellular—outside of neurons—glutamate via a few different ways. One is an “exchange” molecule, which maintains an optimal level of glutamate inside and outside neurons; another is the number of receptors themselves. In any case, when levels of glutamate become off-balance, addictive behavior trumps so-called reason: cravings and relapse result.

A number of research studies have implicated glutamate dysfunction in addiction. In a 2002 study, David Baker, then at the Medical University of South Carolina and now at Marquette University in Wisconsin, found that repeated administration of cocaine in rats lowered glutamate levels. A paper the following year showed that these changes underlie relapse in cocaine users. In 2009, Kalivas published a study in rats that showed treatment with NAC re-activated stalled glutamate pumps and restored glutamate levels to normal. In 2011, he found that NAC treatment not only restored synaptic plasticity, but that it could be tied to less relapse behavior in rats. 

“When glutamate transmission is in balance, we can learn; when it’s out of balance, we can’t learn,” Kalivas says. This is called synaptic plasticity, and in addiction, this flexibility of our brain circuits to adapt to change all but dries up. 

NAC—on trial

While the FDA approved NAC for treating specific conditions unrelated to addictive disorders over 50 years ago, some recent preliminary clinical trials suggest that NAC could be useful in the treatment of many other disorders, including SUDs.

Kevin Gray, also a professor and researcher at the Medical University of South Carolina, led the first randomized controlled trial for treating marijuana addiction, and they published their results in 2012. The trial involved cannabis-dependent adolescents, and participants received either 1200 mg NAC or a placebo twice daily throughout the 8-week treatment. They found that those who received NAC had more than twice the odds of achieving marijuana abstinence—reflected in “clean” urine drug tests—than those who received placebo. It is important to note that subjects received traditional behavioral treatment along with their dose of NAC.

“Given the controlled nature of the trial, we feel it reflects a real effect of NAC in enhancing response to behavioral treatment,” Gray says. “It targets one of many factors involved in addiction—nobody has, to date, tested whether it could work as a standalone treatment. For now, the evidence indicates that it is a helpful complement to psychosocial [or] behavioral treatment.” His group is currently conducting a follow-up study of sorts, across multiple sites and spanning 12 weeks, to test how NAC affects treatment success of cannabis-dependent adults.

Clinical trials for using NAC to treat relapse in cocaine addicts have also shown promising, albeit mixed, results. This is important because currently, there are no medications to treat cocaine and stimulant addiction. In a trial published in 2013, researchers tested the effect of NAC on treating cocaine addicts. The study, led by Robert Malcolm, also at MUSC, found that among users who received either 1200 milligrams NAC, 2400 milligrams NAC, or a placebo on a daily basis over the course of eight weeks, only subjects who were already abstinent had longer times to relapse and lower cravings if they were taking the 2400 milligrams. This suggests that NAC may be useful in preventing relapse among cocaine addicts who have already gotten sober, says Kalivas, who was involved with the trial study. In fact, they’ve already begun a trial along these lines. 

Not a cure-all 

To be sure, a supplement like NAC isn’t going to be a cure-all. As Kalivas says, “cure is a little strong of a word.” NAC works by ultimately increasing the amount of glutamate available to neurons—and, the more glutamate, the better signal transmission and the easier it becomes for addicts to break habits and learn new behaviors. “Basically it resets synapses and so they now have the opportunity to learn.” And while it may enable recovery, it won’t make any difference if an addict doesn’t change his lifestyle.

Trials have focused on determining the efficacy of using NAC in conjunction with traditional therapies, not as a replacement. “The reason for this whole line of research is the limited—[even] poor—abstinence outcomes with existing psychosocial [or] behavioral treatments,” Gray says. “We see NAC as a strong candidate for safe pharmacological augmentation of psychosocial treatment for substance use disorders.”

While he and others prescribe it to their patients “off-label,” some specialists are reluctant. “I don’t prescribe it since it is not FDA approved for this indication and there hasn’t been a large clinical trial to prove its efficacy yet,” says Khaled Moussawi, previously at MUSC and now a neurology resident at Massachusetts General Hospital, who has done research himself on glutamate and its role in addiction. “All the data we have are preliminary.” And, unfortunately, some don’t see FDA approval in the future: “There will never be FDA approval because why would a company go to those lengths when the supplement is available in every health food store in the country?” says Jon Grant of the University of Chicago, who led a recent trial for using NAC to treat obsessive hair pulling, a condition known as trichotillomania.

Over-the-counter?

NAC can be purchased at any health foods store, but…you might want to consult with your doctor before starting to “pop” any pill, even an antioxidant supplement. According to multiple sources, it seems safe; however, there can be side effects, even if they’re relatively benign: nausea, indigestion, headache, and abdominal pain. It has been suggested that NAC may increase excretion of trace minerals; some evidence, however, suggests that this effect is too minimal to make a real difference. Nutritionists would suggest that individuals taking NAC for an extended period of time should also consider taking a multivitamin supplement.

Oral bioavailability of NAC has been shown to range from a mere 4 to 10 percent. It typically comes in 600-milligram capsules, which is much lower than the doses given in most of the clinical trials—it doesn’t necessarily have to be delivered orally, but that’s what’s safest and available to consumers at the moment. Given those two facts, it might not work at all.

There can be dangers to taking too much of it, as well as with other medications. According to the University of Maryland Medical Center, recommended adult doses of NAC vary depending on the health condition being treated; however, very high doses (more than 7 grams) of cysteine may be toxic. UMM also advises against drug-drug interactions. If you are being treated with medications that suppress the immune system (azathioprine (Imuran), cyclophosphamide (Cytoxan), or prednisone (Deltasone)); nitroglycerin and isosorbide (Isordil), two medications commonly used to treat chest pain; oxiconazole (Oxistat), an antifungal medication used for athlete’s foot; or activated charcoal; you should not use cysteine supplements without first talking to your doctor.

Jeanene Swanson is a regular contributor to The Fix. She last wrote about mental disorders and addiction.