Gene Mutations Linked With Increased Risk of Dying From Cocaine Abuse
New research suggests people with common genetic mutations
have an almost eightfold increased risk of dying from cocaine abuse. The
mutations affect the chemical messenger dopamine in the brain.
Dopamine is vital to the functioning of the central nervous system.
Cocaine blocks transporters in the brain from absorbing dopamine, HealthDay reports.
The mutations are found on two genes. The Ohio State University
researchers found about one in three white people who died of cocaine
abuse had these genetic mutations. A different combination of mutations
affects the risk of dying from cocaine abuse in black people, the
researchers noted in a news release.
The study appears in the journal Translational Psychiatry.
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