By Join Together Staff | April 13, 2012 | Leave a comment | Filed inPrescription Drugs & Prevention
Scientists are working to make prescription painkillers and other commonly misused drugs “unabusable” by reformulating them, according to Nora Volkow, Director of the National Institute on Drug Abuse.
Pharmaceutical companies have an important role to play in fighting prescription drug abuse, by reformulating commonly abused drugs, she said at the National Rx Drug Abuse Summit in Orlando, Florida.
Purdue Pharma, maker of OxyContin, released a new version of the drug two years ago that is resistant to crushing and cutting, common ways in which the drug was tampered with to enhance its effect. It is now much more difficult to prepare for snorting or injecting, a company spokeswoman told the Orlando Sentinel.
Acura Pharmaceuticals has developed two methods to prevent tampering with pills, according to CEO Bob Jones. The company has incorporated a substance in pills that turns them into a gel when someone tries to dissolve the drug to inject, so that it will not go through a needle.
The company also has formulated pills so that they create intense nasal irritation when they are crushed and snorted. This formulation is incorporated into the drug Oxecta, an immediate-release oxycodone product, the article notes. Acura plans to use the formulation in other painkillers, Jones said.
Acura has developed technology that limits how much of the key ingredient in methamphetamine a person can extract from the nasal decongestant pseudoephedrine. The technology, which is not yet commercially available, cuts the yield in half.
Drug companies also are creating pills with the consistency of gummy bears, which are too soft to crush. Some drugs in development won’t work unless they come into contact with the stomach’s digestive enzymes, making them useless if they are snorted or injected.
'Tweaking memories' could help addicts avoid relapsingBy James GallagherHealth and science reporter, BBC News
Can memories of drug use be rewritten?
Continue reading the main story
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Manipulating memories of drug use may help reformed addicts avoid a return to a life of drug abuse, according to scientists in China.
They said memories linking "cues" - such as needles or cigarettes - and the pleasurable effects of drugs caused cravings and relapsing.
Authors of the study, published in the journal Science, "rewrote" those memories to reduce cravings.
Experts said targeting memories could become a new avenue for treatment.
Repeatedly showing people drug cues without actually giving patients the drug is a part of some therapies for addicts. It can break the link between cue and craving in the clinic. But this does not always translate to real life.
The researchers at Peking University tried to rewrite the original memory so that it would be as if the link between cue and the craving never existed.Flexible memories
The work relies on the idea that a memory can become malleable after it is accessed, creating a brief window during which the memory can be "rewritten".
Continue reading the main story
“Start Quote
I'm quite excited by this research... It could be really important for treatment of addiction”Dr Amy MiltonUniversity of Cambridge
Twenty-two heroin addicts who had not taken the drug for - on average - 11 years, took part in the study.
They were initially shown a brief video to remind them of taking drugs - opening the memory window. Ten minutes later they watched more videos and looked at pictures of heroin drug use.
Other addicts were shown an initial video of the countryside, which would not open the window.
Tests 180 days later showed that levels of cravings were lower in those treated during the 'memory window' than in the other groups. These experiments were backed up by further tests on "addicted" rats.
The authors wrote: "The [memory] procedure decreased cue-induced drug craving and perhaps could reduce the likelihood of cue-induced relapse during prolonged abstinence periods."
Dr Amy Milton, who researches memory and addiction at the University of Cambridge, said: "I'm quite excited by this research."
She said it was "such a minor" difference from current therapies which "tapped into an entirely different memory process" and the reconstruction of the original memory.
"Full clinical studies are needed, but it could be really important for treatment of addiction," she said.
Dr Milton added: "There is no theoretical reason it couldn't apply to other addictions such as alcohol. That's obviously very exciting."
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Dear Joseph,
Inspirational, motivational, educational.
These are just a few words that could describe the amazing work by former professional basketball player and father Chris Herren, celebrating three and a half years in recovery from a drug and alcohol addiction.
The Partnership at Drugfree.org is honored that Chris will host the next "Meet The Parents Hour" -- a live Facebook Q&A chat -- to talk about substance abuse recovery on Monday, April 16 at 12 p.m. EDT/9 a.m. PDT.
To make sure everyone has the chance to ask his or her question, submit yours in advance, and Chris will do his best to get to it during the session.
Submit your question to Chris Herren now.
Chris struggled with drug addiction for much of his basketball career and ultimately realized his dreams by playing for the Boston Celtics in the NBA, only to lose it all to substance abuse.
But since losing one dream, he has been able to rise again with a new one; a life of sobriety.
Drug- and alcohol-free since 2008, Chris now travels the country sharing his story and the experiences that led him to recovery with the hopes of reaching one person or assisting a family who may be facing a loved one's addiction. He also runs The Herren Project, a nonprofit foundation established in 2011 that assists individuals and families struggling with addiction.
Don't miss out on this special opportunity to chat live with Chris Herren and hear his story. Submit your questions now and then visit our Facebook timeline on April 16 to take part in the live chat:
http://my.drugfree.org/questions-for-chris
We look forward to seeing you at our next "Meet The Parents Hour."
Thank you,
Tom Hedrick
Parent Support Leader
The Partnership at Drugfree.org
P.S. If you haven't Liked us yet on Facebook, do it now so you can participate in the live chat session.
Dear RIR Friends,
"RIR Band members Ricky Byrd, Liberty DeVitto, and Christine Ohlman are off to Cleveland to prepare for the April 13 Rock n' Roll Hall Of Fame Pre-Induction Gala.
Ricky and Christine will also join Paul Shaffer and Carole King in inducting Don Kirshner at the April 14 induction ceremony, filmed for May 5 premier on HBO.
Watch for more information on the May 5 premier on HBO:
http://www.hbo.com/the-rock-and-roll-hall-of-fame-2012-induction-ceremony/about/index.html
Ricky Byrd, Liberty DeVitto, and Christine Ohlman along with the rest of the RIR Band looks forward to seeing everyone May 26, 2012 for the RIR 2nd Annual Concert and Picnic. Venue 1St Step Sober House of Pompano Beach. This concert and picnic is sponsored by Treatment Solutions Network and Miami Subs and Grill.
Meet The RIR Band: http://www.rirconcerts.com/rir-all-star-band/
Love & Peace,
John Hollis
RIR CONCERTS
If your interested in becoming a sponsor for the May 26 concert, please call John Hollis at 954-826-4920 or Email john@rockersinrecovery.com no later then May 1,2012.
Millions of people are struggling with drug or alcohol addiction every day. Finding the appropriate addiction rehab has always been a challenge. We understand how important it is for you to find a treatment facility that is most equipped to treat your disease. A licensed facility with doctors, nurses , therapists and recovery coaches on staff with experience in substance abuse and dual diagnosis treatment.
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Name/Address/Phone Type of
Ownership Last
Inspection Activity (Added On) -
Client capacity -
License Status
HARBOR COUNSELING
(HARBOR COUNSELING, INC.)
7095 ROUTE 287
WELLSBORO PA 16901
(570)724-5272
(Open)
Additional Services Non-Profit 08/25/2011 Outpatient Drug-Free (05/08/1992)
Client Capacity: 80
License Status: Full
Partial Hospitalization Drug-Free (09/28/1994)
Client Capacity: 30
License Status: Full
SEABROOK HOUSE, INC.
355 CHURCH STREET
WESTFIELD PA 16950
(814)367-2003
(Open)
Additional Services Non-Profit 03/24/2011 Inpatient Non-Hospital Drug-Free Transitional Living Facility (12/20/2007)
Client Capacity: 28
License Status: Full
SOLDIERS AND SAILORS MEMORIAL HOSPITAL
(Soldiers & Sailors Memorial Hospital)
32-36 CENTRAL AVENUE
WELLSBORO PA 16901
(570)724-1631
(Open)
Additional Services Non-Profit 08/01/2011 Inpatient Hospital Detoxification (02/07/1985)
Client Capacity: 4
License Status: Full
TIOGA COUNTY HUMAN SERVICES AGENCY
(Tioga County Commissioners)
ST. JAMES COMPLEX
St. James and Third Streets, Building A, Suite 109
MANSFIELD PA 16933
(570)662-7600
(Closed)
Additional Services Non-Profit 01/26/2011 Outpatient Drug-Free (09/02/1997)
Client Capacity: 107
License Status: Full
